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For more significant breakouts of pimples more than 5 10 of your face priligy over the counter The causes of thrombocytopenia include reduced platelet production in the bone marrow, drug induced thrombocytopenia, leukemia, deficiency in vitamin B12 and folate, cirrhosis liver disease, enlarged spleen, immune thrombocytopenia a disorder that causes the immune system to attack platelets, and thrombotic thrombocytopenic purpura abnormal clotting that leads to lower platelet count